Treatments and drugs
By Mayo Clinic staffIn most cases, pityriasis rosea goes away on its own in four to six weeks. In some cases, your doctor may treat the rash. But pityriasis rosea treatment usually focuses on controlling itching.
Treating the rash
- Antiviral medications. The antiviral drugs acyclovir (Zovirax) and famciclovir (Famvir) may reduce the duration of pityriasis rosea by one to two weeks.
- Light therapy (phototherapy). This therapy may lessen the duration of pityriasis rosea, and can be done with ultraviolet B (UVB) light or sunlight. Talk to your doctor before using sunlight to treat your rash. UVB therapy is most often available at your doctor's office. Light phototherapy may cause lasting darkening in certain spots, even after the rash clears.
Relieving itching
If itching is a problem, your doctor may recommend the following to provide relief:
- Steroid creams or ointments. These creams will help ease itching and decrease redness.
- Oral antihistamines. These medications are available by prescription as cetirizine (Zyrtec) and fexofenadine (Allegra), and over-the-counter as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), clemastine (Tavist) and loratadine (Claritin).
- Pityriasis rosea. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec10/ch116/ch116d.html. Accessed Feb. 12, 2010.
- Goldstein AO, et al. Pityriasis rosea. http://www.uptodate.com/home/index.html. Accessed Jan. 29, 2010.
- Drago F, et al. Pityriasis rosea: An update with a critical appraisal of its possible herpesviral etiology. Journal of the American Academy of Dermatology. 2009;61:303.
- Chuh AA, et al. Interventions for pityriasis rosea. Cochrane Database of Systematic Reviews. 2007;2:CD005068.
- Blauvelt A. Pityriasis rosea. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2955172. Accessed Feb. 12, 2010.

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