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Prevention

By Mayo Clinic staff

Although no effective vaccine is available, scientists are working to develop one. Antibiotics can help prevent infection if you're at risk of or have been exposed to plague. Take the following precautions if you live or spend time in regions where plague outbreaks occur:

  • Rodent-proof your home. Remove potential nesting areas, such as piles of brush, rock, firewood and junk. Don't leave pet food in areas that rodents can easily access.
  • Keep your pets free of fleas. Ask your veterinarian which flea-control products will work best.
  • Use insect repellent. Closely supervise your children and pets when spending time outside in areas with large rodent populations. Use insect repellent.
References
  1. Plague. Centers for Disease Control and Prevention. http://www.cdc.gov/plague/. Accessed Dec. 21, 2012.
  2. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Dec. 21, 2012.
  3. Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 24, 2012.
  4. Sun W, et al. Developing live vaccines against Yersinia pestis. Journal of Infection in Developing Countries. 2011;5:614.
  5. Butler T. Plague into the 21st century. Clinical Infectious Diseases. 2009;49:736.
  6. Amedei A, et al. Role of immune response in Yersinia pestis infection. Journal of Infection in Developing Countries. 2011;5:628.
  7. FDA approves new antibacterial treatment for plague. FDA news release. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm302220.htm. Accessed Dec. 24, 2012.
DS00493 March 26, 2013

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