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Tests and diagnosis

By Mayo Clinic staff

If your doctor suspects plague, he or she may look for the Yersinia pestis bacteria in samples taken from your:

  • Buboes. If you have the swollen lymph nodes (buboes) characteristic of bubonic plague, a fluid sample can be taken from them with a needle.
  • Blood. Yersinia pestis bacteria generally are present in your bloodstream only if you have septicemic plague.
  • Lungs. To check for pneumonic plague, your doctor will take sputum or fluid from your airways using endoscopy — a thin, flexible tube inserted through your nose or mouth and down your throat.
References
  1. Plague. Centers for Disease Control and Prevention. http://www.cdc.gov/plague/. Accessed Dec. 21, 2012.
  2. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Dec. 21, 2012.
  3. Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 24, 2012.
  4. Sun W, et al. Developing live vaccines against Yersinia pestis. Journal of Infection in Developing Countries. 2011;5:614.
  5. Butler T. Plague into the 21st century. Clinical Infectious Diseases. 2009;49:736.
  6. Amedei A, et al. Role of immune response in Yersinia pestis infection. Journal of Infection in Developing Countries. 2011;5:628.
  7. FDA approves new antibacterial treatment for plague. FDA news release. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm302220.htm. Accessed Dec. 24, 2012.
DS00493 March 26, 2013

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