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Definition
By Mayo Clinic staffPlague was known as the Black Death during medieval times, when it killed up to a third of the population of Europe. Currently, plague occurs in fewer than 3,000 people per year worldwide. It can be deadly if not treated promptly with antibiotics.
The organism that causes plague, Yersinia pestis, lives in a variety of small rodents on every continent except Australia. The organism is transmitted to humans when they are bitten by fleas that have previously fed on infected rodents.
The most common form of plague results in swollen and tender lymph nodes — called buboes — in the groin, armpits or neck. The rarest and deadliest form of plague affects the lungs, and it can be spread from person to person.
- Everett ED. Microbiology, pathogenesis and epidemiology of plague (Yersinia pestis infection). http://www.uptodate.com/home/index.html. Accessed June 17, 2010.
- Gage KL. Plague and other Yersinia infections. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/206594927-5/1015859897/1492/1167.html#4-u1.0-B978-1-4160-2805-5..50338-4_14426. Accessed June 17, 2010.
- Everett ED. Clinical manifestations, diagnosis and treatment of plague (Yersinia pestis infection). http://www.uptodate.com/home/index.html. Accessed June 17, 2010.
- Plague fact sheet. National Park Service. http://www.nps.gov/public_health/info/factsheets/fs_plague.htm. Accessed June 18, 2010.
- Frequently asked questions (FAQ) about plague. Centers for Disease Control and Prevention. http://www.bt.cdc.gov/agent/plague/faq.asp. Accessed June 18, 2010.
- Information on plague. Center for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/plague.info.htm. Accessed June 18, 2010.
- Interregional meeting on prevention and control of plague. World Health Organization. http://www.who.int/csr/resources/publications/WHO_HSE_EPR_2008_3w.pdf. Accessed June 21, 2010.
- Plague fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvbid/plague/qa.htm. Accessed June 21, 2010.
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