Polycystic ovary syndrome

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Complications

By Mayo Clinic staff

Having polycystic ovary syndrome makes the following conditions more likely, especially if obesity also is a factor:

  • Type 2 diabetes
  • High blood pressure
  • Cholesterol abnormalities, such as high triglycerides or low high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol
  • Elevated levels of C-reactive protein, a cardiovascular disease marker
  • Metabolic syndrome, a cluster of signs and symptoms that indicate a significantly increased risk of cardiovascular disease
  • Nonalcoholic steatohepatitis, a severe liver inflammation caused by fat accumulation in the liver
  • Sleep apnea
  • Abnormal uterine bleeding
  • Cancer of the uterine lining (endometrial cancer), caused by exposure to continuous high levels of estrogen
  • Gestational diabetes or pregnancy-induced high blood pressure, if you do become pregnant
References
  1. Wilson EE. Polycystic ovarian syndrome and hyperandrogenism. In: Schorge JO, et al. Williams Gynecology. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aid=3157034. Accessed June 22, 2009.
  2. Barbieri RL, et al. Clinical manifestations of polycystic ovary syndrome in adults. http://www.uptodate.com/home/index.html. Accessed June 22, 2009.
  3. Ehrmann DA. Polycystic ovary syndrome. New England Journal of Medicine. 2005;352:1223.
  4. Azziz RA, et al. The androgen excess and PCOS society criteria for the polycystic ovary syndrome: The complete task force report. Fertility and Sterility. 2009;91:456.
  5. Polycystic ovary syndrome (PCOS): Frequently asked questions. U.S. Department of Health and Human Services Office on Women's Health. http://www.4woman.gov/faq/pcos.pdf. Accessed June 16, 2009.
  6. Guzick DS. Polycystic ovary syndrome. Obstetrics & Gynecology. 2004;103:181.
  7. Radosh L. Drug treatments for polycystic ovary syndrome. American Family Physician. 2009;79:671.
  8. Barbieri RL, et al. Treatment of polycystic ovary syndrome in adults. http://www.uptodate.com/home/index.html. Accessed June 22, 2009.
  9. Tapanainen JS, et al. Effective regimens for ovulation induction in polycystic ovary syndrome. In: Dunaif A, et al. Polycystic Ovary Syndrome: Current Controversies, From the Ovary to the Pancreas. Totowa, N.J.: Humana; 2008:307.
  10. Gonzalez F (expert opinion). Mayo Clinic, Rochester, Minn. July 3, 2009.

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July 31, 2009

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