Causes
By Mayo Clinic staffSome experts believe post-concussion symptoms are caused by structural damage to the brain or disruption of neurotransmitter systems, resulting from the impact that caused the concussion. Others believe post-concussion symptoms are related to psychological factors, especially since the most common symptoms — headache, dizziness and sleep problems — are similar to those often experienced by people diagnosed with depression, anxiety or post-traumatic stress disorder. In many cases, both physiological effects of brain trauma and emotional reactions to these effects play a role in the development of symptoms.
Researchers haven't determined why some people who've had concussions develop persistent post-concussion symptoms while others do not. No proven correlation between the severity of the injury and the likelihood of developing persistent post-concussion symptoms exists.
- Evans RW. Post-concussion syndrome. http://www.uptodate.com/home/index.html. Accessed June 4, 2011.
- Wright DW, et al. Head trauma in adults and children. In: Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/content.aspx?aid=6388784. Accessed June 1, 2011.
- Jotwani V, et al. Postconcussion syndrome in athletes. Current Sports Medicine Reports. 2010;9:21.
- DeLee JC, et al. Head injuries. In: DeLee JC, et al. DeLee and Drez's Orthopaedic Sports Medicine. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2009. http://www.mdconsult.com/books/page.do?sid=1168525515&eid=4-u1.0-B978-1-4160-3143-7..10015-6--s0015&isbn=978-1-4160-3143-7&uniqId=257618564-3. Accessed June 1, 2011.
- Prigatano GP, et al. The current status of postconcussion syndrome. Current Opinion in Psychiatry. 2011;24:243.
- Traumatic brain injury: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/tbi/detail_tbi.htm. Accessed June 4, 2011.
- What you need to know about air bags. National Highway Traffic Safety Administration. http://www.nhtsa.gov/people/injury/airbags/airbags03/airbags1.html#1065115450. Accessed July 13, 2011.
- Cicerone KD, et al. Evidence-based cognitive rehabilitation: Updated review of the literature from 2003 through 2008. Archives of Physical Medicine and Rehabilitation. 2011;92:519.


Find Mayo Clinic on