Post-polio syndrome

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Risk factors

By Mayo Clinic staff

Factors that may increase your risk of developing post-polio syndrome include:

  • Severity of initial polio infection. The more severe the initial infection, the more likely that you'll have signs and symptoms of post-polio syndrome.
  • Age at onset of initial illness. If you acquired polio as an adolescent or adult, rather than as a young child, your chances of developing post-polio syndrome increase.
  • Recovery. The greater your recovery after acute polio, the more likely it seems that post-polio syndrome will develop. This may be because greater recovery places additional stress on motor neurons.
  • Physical activity. If you often perform physical activity to the point of exhaustion or fatigue, this may overwork already stressed-out motor neurons and increase your risk of post-polio syndrome.
  • Gender. Females are more likely to develop post-polio syndrome.
References
  1. Boyer FC, et al. Post-polio syndrome: Pathophysiological hypotheses, diagnosis criteria, medication therapeutics. Annals of Physical and Rehabilitation Medicine. 2010;53:34.
  2. Simionescu L, et al. Post-polio syndrome. http://www.uptodate.com/home/index.html. Accessed Dec. 16, 2010.
  3. Post-polio syndrome — polio's legacy. Clinical Medicine. 2010;10:213.
  4. Post-polio syndrome fact sheet, National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/post_polio/detail_post_polio.htm. Accessed Jan. 15, 2011.
  5. Tiffreau V, et al. Post-polio syndrome and rehabilitation. Annals of Physical and Rehabilitation Medicine. 2010;53:42.
DS00494 March 3, 2011

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