Free

E-Newsletters

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Causes

By Mayo Clinic staff

Any factor that increases pressure against the artery walls can lead to prehypertension. Atherosclerosis, which is the buildup of fatty deposits in your arteries, can lead to high blood pressure. Sometimes an underlying condition causes blood pressure to rise. Possible conditions that can lead to prehypertension or high blood pressure include:

  • Atherosclerosis
  • Sleep apnea
  • Kidney disease
  • Adrenal disease
  • Thyroid disease

Certain medications — including birth control pills, cold remedies, decongestants, over-the-counter pain relievers and some prescription drugs — also may cause blood pressure to temporarily rise. Illegal drugs, such as cocaine and amphetamines, can have the same effect.

Often, however, high blood pressure develops gradually over many years without a specific identifiable cause.

References
  1. Svetkey LP. Management of prehypertension. Hypertension. 2005;45:1056.
  2. What are high blood pressure and prehypertension? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/hbp/hbp/whathbp.htm. Accessed April 8, 2010.
  3. Liszka HA, et al. Prehypertension and cardiovascular morbidity. Annals of Family Medicine. 2005;3:294.
  4. Green L. Prehypertension, patient outcomes, and the knowledge base of family medicine. Annals of Family Medicine. 2005;3:292.
  5. Chobanian AV, et al. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Hypertension. 2003;42:1206.
  6. Schunkert H. Pharmacotherapy for prehypertension — Mission accomplished? New England Journal of Medicine. 2006;354:1742.
  7. Julius S, et al. Feasibility of treating prehypertension with an angiotensin-receptor blocker. New England Journal of Medicine. 2006;354:1685.
  8. Karanja N, et al. Acceptability of sodium-reduced research diets, including the dietary approaches to stop hypertension diet, among adults with prehypertension and stage 1 hypertension. Journal of the American Dietetic Association. 2007;107:1530.
  9. Maruthur NM, et al. Lifestyle interventions reduce coronary heart disease risk: Results from the PREMIER trial. Circulation. 2009;119:2026.
  10. Pimenta E, et al. Prehypertension: Epidemiology, consequences and treatment. Nature Review Nephrology. 2010;6:21.
  11. Dietary Guidelines for Americans, 2010. U.S. Department of Health and Human Services. http://www.cnpp.usda.gov/DGAs2010-PolicyDocument.htm. Accessed Feb. 18, 2011.
DS00788 March 22, 2011

© 1998-2012 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Advertisement


Text Size: smaller largerlarger