Premature ovarian failure

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Risk factors

By Mayo Clinic staff

Factors that increase your risk of developing premature ovarian failure include:

  • Age. The risk of ovarian failure rises sharply between age 35 and age 40.
  • Family history. Having a family history of premature ovarian failure increases your risk of developing this disorder.
Complications Causes

  • See Also

    • Hand Scheduled
    Section Focus
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    Children
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  • Menopause
References
  1. Rebar RW. Premature ovarian failure. Obstetrics & Gynecology. 2009;113:1355.
  2. Do I have premature ovarian failure (POF)? National Institute of Child Health and Human Development. http://www.nichd.nih.gov/publications/pubs/pof/index.cfm. Accessed Nov. 16, 2010.
  3. Lobo RA. Menopause: Endocrinology, consequences of estrogen deficiency, effects of hormone replacement therapy, treatment regimens. In: Katz VL, et al. Comprehensive Gynecology. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/208746819-4/0/1524/0.html. Accessed Nov. 16, 2010.
  4. Welt CK. Pathogenesis and causes of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 15, 2010.
  5. Bulun SE, et al. The physiology and pathology of the female reproductive axis. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191205553-3/0/1555/0.html#. Accessed Nov. 16, 2010.
  6. Kalu E, et al. Spontaneous premature ovarian failure: Management challenges. Gynecological Endocrinology. 2008;24:273.
  7. Nelson LM, et al. Evaluation of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 15, 2010.
  8. Nelson LM, et al. Management of spontaneous premature ovarian failure. http://www.uptodate.com/home/index.html. Accessed Nov. 15, 2010.
  9. Coddington CC (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 29, 2010.
  10. Dietary Reference Intakes for calcium and vitamin D. Institute of Medicine. http://www.iom.edu/vitamind. Accessed Dec. 10, 2010.
DS00843 Dec. 30, 2010

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