Prescription drug abuse

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Symptoms

By Mayo Clinic staff

Signs and symptoms of prescription drug abuse depend on the particular drug. Because of their mind-altering properties, the most commonly abused prescription drugs are:

  • Opioids, such as oxycodone (Oxycontin) and those containing hydrocodone (Vicodin), used to treat pain
  • Anti-anxiety medications and sedatives, such as alprazolam (Xanax) and diazepam (Valium), and hypnotics, such as zolpidem (Ambien), used to treat anxiety and sleep disorders
  • Stimulants, such as methylphenidate (Ritalin), used to treat ADHD and certain sleep disorders

Signs and symptoms of prescription drug abuse

Opioid painkillersSedatives and anti-anxiety medicationsStimulants
  • Constipation
  • Depression
  • Low blood pressure
  • Decreased breathing rate
  • Confusion
  • Sweating
  • Poor coordination
  • Drowsiness
  • Confusion
  • Unsteady walking
  • Poor judgment
  • Involuntary and rapid movement of the eyeball
  • Dizziness
  • Weight loss
  • Agitation
  • Irritability
  • Insomnia
  • High blood pressure
  • Irregular heartbeat
  • Restlessness
  • Impulsive behavior

Other signs include:

  • Stealing, forging or selling prescriptions
  • Taking higher doses than prescribed
  • Excessive mood swings or hostility
  • Increase or decrease in sleep
  • Poor decision making
  • Appearing to be high, unusually energetic or revved up, or sedated
  • Continually "losing" prescriptions, so more prescriptions must be written
  • Seeking prescriptions from more than one doctor

When to see a doctor
Talk to your doctor if you think you may have a problem with prescription drug use. You may feel embarrassed to talk to your doctor about it — but remember that medical professionals are trained to help you, not judge you. Identifying prescription drug abuse as soon as possible is important. It's easier to tackle the problem early before it becomes an addiction and leads to more serious problems.

References
  1. Parran TV. Prescription drug abuse and addiction: Clinical features, epidemiology, and contributing factors. http://www.uptodate.com/index. Accessed Aug. 23, 2012.
  2. NIDA DrugFacts: Prescription and over-the-counter medications. National Institute on Drug Abuse. http://www.drugabuse.gov/infofacts/PainMed.html. Accessed Aug. 23, 2012.
  3. Epidemic: Responding to America's prescription drug abuse crisis. Office of National Drug Control Policy. http://www.whitehousedrugpolicy.gov/drugfact/prescrptn_drgs/rx_ff.html. Accessed Aug. 23, 2012.
  4. Commonly abused prescription drugs. Office of National Drug Control Policy. http://www.drugabuse.gov/DrugPages/PrescripDrugsChart.html. Accessed Aug. 23, 2012.
  5. Prescription drugs: Abuse and addiction. National Institute on Drug Abuse. http://www.drugabuse.gov/researchreports/prescription/prescription6.html. Accessed Aug. 23, 2012.
  6. Gunter WD, et al. Desisting from prescription drug abuse: An application of growth models to Rx opioid users. Journal of Drug Issues. 2012;42:82.
  7. Prescription drug abuse. The Nemours Foundation. http://kidshealth.org/teen/drug_alcohol/drugs/prescription_drug_abuse.html. Accessed Aug. 24, 2012.
  8. Colson J, et al. Office-based opioid dependence treatment. Pain Physician. 2012;15:ES231.
  9. Disposal of unused medicines: What you should know. U.S. Food and Drug Administration. http://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/EnsuringSafeUseofMedicine/SafeDisposalofMedicines/ucm186187.htm#MEDICINES. Accessed Sept. 27, 2012.
  10. Koechl B, et al. Age-related aspects of addiction. Gerontology. In press. Accessed Aug. 24, 2012.
  11. Sehgal N, et al. Prescription opioid abuse in chronic pain: A review of opioid abuse predictors and strategies to curb opioid abuse. Pain Physician. 2012;15:ES67.
  12. Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 5, 2012.
  13. Schneekloth TD (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 19, 2012.
  14. Intervention — Tips and guidelines. National Council on Alcoholism and Drug Dependence. http://www.ncadd.org/index.php/for-friends-and-family/intervention. Accessed Sept. 28, 2012.
DS01079 Oct. 11, 2012

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