ComplicationsBy Mayo Clinic staff
Although the average progression of primary lateral sclerosis lasts around 20 years, the disease has highly variable effects from person to person. Some people may be able to continue to walk, but others will eventually need wheelchairs or other assistive devices for mobility or other activities.
Adult PLS isn't considered to shorten life expectancy, but it may gradually affect the quality of your life as more muscles become disabled. Weaker muscles may cause you to fall more, which may result in injuries.
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- Motor neuron diseases fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/motor_neuron_diseases/detail_motor_neuron_diseases.htm. Accessed Aug. 17, 2010.