Primary progressive aphasia


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Complications

By Mayo Clinic staff

People with primary progressive aphasia may become mute and may eventually lose the ability to understand written and spoken language.

As the disease progresses, other mental skills, such as memory, may become impaired. Some people may develop other neurological conditions over time. If these complications occur, the affected person eventually will need help with day-to-day care.

People with primary progressive aphasia may also develop behavioral or social problems, such as being anxious or irritable. Other problems may include blunted emotions, poor judgment or inappropriate social behavior.

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References
  1. Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=54. Accessed Oct. 12, 2012.
  2. Gorno-Tempini ML, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76:1006.
  3. Harciarek M, et al. Primary progressive aphasias and their contribution to the contemporary knowledge about the brain-language relationship. Neuropsychology Review. 2011;21:271.
  4. NINDS frontotemporal dementia information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/picks/picks.htm. Accessed Oct. 12, 2012.
  5. Rogalski E, et al. Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives. Archives of Neurology. 2008;65:244.
  6. Approach to the patient with aphasia. http://www.uptodate.com/index. Accessed Oct. 12, 2012.
  7. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 24, 2012.
  8. Aphasia. National Institute on Deafness and Other Communication Disorders. http://www.nidcd.nih.gov/health/voice/pages/aphasia.aspx. Accessed Oct. 29, 2012.
  9. Communicating with people who have aphasia. The National Aphasia Association. http://www.aphasia.org/Aphasia%20Facts/communicating_with_people_who_have_aphasia.html. Accessed Oct. 29, 2012.
  10. Caring for a person with a frontotemporal disorder. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/frontotemporal-disorders-information-patients-families-and-caregivers/caring. Accessed Oct. 31, 2012.
  11. Treatment and management. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/frontotemporal-disorders-information-patients-families-and-caregivers-0. Accessed Oct. 31, 2012.
  12. Boeve BF (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 20, 2012.
  13. Duffy JR (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 26, 2012.
DS00750 Jan. 16, 2013

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