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Tests and diagnosis
By Mayo Clinic staffBecause there is no specific test to diagnose primary progressive aphasia, your doctor will need to rule out other possible causes of your symptoms.
Communication tests
Written and verbal tests pose questions that measure cognitive functions for attention, learning, recall and language. But because these tests depend primarily on language skills, their usefulness declines as the symptoms of primary progressive aphasia worsen.
Blood tests
Doctors may order blood tests to check for other factors that can cause memory loss, such as infections, vitamin deficiencies, anemia, medication levels, and disorders of the thyroid, liver or kidneys.
Brain scans
MRI or CT scans can detect strokes, tumors or other conditions that may affect brain function. SPECT or PET scans can be helpful if other scans do not show any abnormalities.
- Progressive aphasia. The Association for Frontotemporal Dementias. http://www.ftd-picks.org/frontotemporal-dementias/disorders/progressive-aphasia. Accessed May 25, 2010.
- NINDS frontotemporal dementia information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/picks/picks.htm. Accessed May 25, 2010.
- Degenerative diseases of the nervous system. In: Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw Hill: 2009. http://www.accessmedicine.com/content.aspx?aID=3639106&searchStr=aphasia%2c+primary+progressive. Accessed May 25, 2010.
- Semantic dementia. The Association for Frontotemporal Dementias. http://www.ftd-picks.org/frontotemporal-dementias/disorders/semantic-dementia. Accessed May 25, 2010.
- Rogalski E, et al. Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives. Archives of Neurology. 2008;65:24.
- Haugarvoll K, et al. The genetics of frontotemporal dementia. Neurologic Clinics. 2007;25:697.
- Craft S, et al. Cognitive changes associated with normal and pathological aging. In: Halter JB, et al. Hazzard's Geriatric Medicine and Gerontology. 6th ed. New York, N.Y.: McGraw Hill; 2009. http://www.accessmedicine.com/content.aspx?aID=5122009&searchStr=aphasia%2c+primary+progressive#5122009. Accessed May 25, 2010.
- Frontotemproal dementia. The Association for Frontotemporal Dementias. http://www.ftd-picks.org/frontotemporal-dementias/ftd-overview. Accessed May 25, 2010.
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