Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get Started
close window
Housecall Archives
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
close window
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Risk factors
By Mayo Clinic staffFactors that may increase the risk of primary sclerosing cholangitis include:
- Your age. Primary sclerosing cholangitis can occur at any age, but it's most commonly diagnosed in people ages 25 to 45.
- Your sex. Primary sclerosing cholangitis occurs more often in men than it does in women.
- Inflammatory bowel disease. The great majority of people with primary sclerosing cholangitis also have inflammatory bowel disease, which includes ulcerative colitis and Crohn's disease. Still, primary sclerosing cholangitis is rare among people with inflammatory bowel disease, and most won't develop primary sclerosing cholangitis. It's not clear why these diseases occur together. If you've been diagnosed with primary sclerosing cholangitis, your doctor may recommend testing for inflammatory bowel disease, even if you have no signs or symptoms.
References
- Tung BY, et al. Sclerosing cholangitis and recurrent pyogenic cholangitis. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/124031765-2/0/1389/0.html. Accessed March 5, 2009.
- Silveira MG, et al. Clinical features and management of primary sclerosing cholangitis. World Journal of Gastroenterology. 2008;14:3338.
- Lopez MJ, et al. Primary sclerosing cholangitis and primary biliary cirrhosis. The American College of Gastroenterology. http://www.acg.gi.org/patient/gihealth/sclerosing.asp. Accessed March 8, 2009.
- Primary sclerosing cholangitis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/primarysclerosingcholangitis/index.htm. Accessed March 8, 2009.
- Liver health tips. American Association for the Study of Liver Diseases. http://www.aasld.org/yourliver/Pages/LiverHealthTips.aspx. Accessed March 8, 2009.
- Rosenthal TC, et al. Fatigue: An overview. American Family Physician. 2008;78:1173.
