Progressive supranuclear palsy

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Definition Symptoms Causes Tests and diagnosis

Complications Treatments and drugs Lifestyle and home remedies Coping and support

Definition

Progressive supranuclear palsy is a brain disorder that causes serious problems with walking, balance and eye movements. Although the cause is unknown, progressive supranuclear palsy results from deterioration of cells in areas of your brain that control movement.

Progressive supranuclear palsy can be difficult to diagnose because some signs and symptoms — such as stiffness, movement difficulties, and changes in mood or personality — are similar to those of Parkinson's disease and dementia. In fact, because of its similarity to Parkinson's disease, it's considered a "parkinsonism-plus syndrome."

Also known as Steele-Richardson-Olszewski syndrome, progressive supranuclear palsy affects one in every 100,000 adults, usually people older than 60, although it can start as early as age 40. No effective treatment for progressive supranuclear palsy exists. The disease is not life-threatening itself, but it can lead to life-threatening complications such as pneumonia and problems swallowing.

Treatment of progressive supranuclear palsy involves approaches to improve some signs and symptoms as well as lifestyle modifications to accommodate the condition.

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Symptoms