Progressive supranuclear palsy

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Complications

By Mayo Clinic staff

Complications of progressive supranuclear palsy result primarily from hindered muscle movements. These complications may include:

  • Frequent falling, which can lead to head injuries, fractures and other injuries
  • Difficulty focusing your eyes, which also can lead to injuries
  • Problems reading, or with other tasks requiring hand-eye coordination
  • The need for a wheelchair
  • Dependence on others for care
  • Difficulty sleeping
  • Difficulty looking at bright lights
  • Problems swallowing

Swallowing difficulties can lead to choking or inhaling food or liquid into your airway (aspiration). Aspiration can develop into pneumonia — the most common cause of death in people with progressive supranuclear palsy.

References
  1. NINDS progressive supranuclear palsy information page. National Institute of Neurological Disorders and Stroke. www.ninds.nih.gov/disorders/psp/psp_htm?css=print. Accessed Dec. 4, 2008.
  2. Progressive supranuclear palsy fact sheet. National Institute of Neurological Disorders and Stroke. www.ninds.nih.gov/disorders/psp/detail_psp.htm?css=print. Accessed Dec. 4, 2008.
  3. Karceski S. Progressive supranuclear palsy. Neurology. 2008;71:e70.
  4. Borroni B, et al. Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy. Neurology. 2008;71:1796.
  5. PSP: Some answers. Society for Progressive Supranuclear Palsy. http://www.psp.org/doc_library/1217970611/Some%20Answers.pdf. Accessed Jan.18, 2009.
  6. Treatments for progressive supranuclear palsy. Worldwide Education and Awareness for Movement Disorders. http://www.wemove.org/psp/psp_tre.html. Accessed Dec. 4, 2008.
  7. Josephs KA, et al. Diagnostic accuracy of progressive supranuclear palsy in the Society for Progressive Supranuclear Palsy brain bank. Movement Disorders. 2003;18:1018.
  8. Josephs, KA. (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 21, 2009.

DS00909

March 24, 2009

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