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  • With Mayo Clinic medical oncologist

    Timothy Moynihan, M.D.

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Mayo Clinic Health Manager

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Question

Prostate cancer vaccine: Is it available?

I've heard there is a prostate cancer vaccine? Is that true and where can I get it?

Answer

from Timothy Moynihan, M.D.

Researchers are working on a prostate cancer vaccine, but no prostate cancer vaccine has yet been approved by the Food and Drug Administration for use in the general population. The prostate cancer vaccines currently in development are only available to men participating in clinical trials. One or more of the vaccines may be approved for wider use within the next few years.

Some vaccines target viruses — such as polio or influenza — and are designed to prevent a disease in otherwise healthy individuals. In contrast, the prostate cancer vaccines in development are therapeutic vaccines. They're designed to be given to men who already have prostate cancer to treat the cancer and to prevent it from spreading.

Prostate cancer vaccines help the body's immune system to recognize prostate cancer cells and to attack and destroy them. The vaccines use a number of mechanisms to do this. There's also some evidence that these vaccines have minimal side effects.

Talk with your doctor about whether participating in a clinical trial might be appropriate for you. You can also find out more about cancer clinical trials by going to the National Cancer Institute's Clinical Trials Web page.

Next question
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References
  1. What's new in prostate cancer research and treatment? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_6X_Whats_New_in_Prostate_Cancer_Research_and_Treatment_36.asp. Accessed Feb. 10, 2009.
  2. Cancer vaccine fact sheet. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/cancervaccine. Accessed Feb. 11, 2009.
  3. Mohebtash M, et al. Therapeutic prostate cancer vaccines: A review of the latest developments. Current Opinion in Investigational Drugs. 2008;9:1296.
  4. Mohebtash M, et al. Cancer vaccines: Current directions and perspectives in prostate cancer. Current Opinion in Molecular Therapeutics. 2009;11:31.

AN01978

March 25, 2009

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