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Complications

By Mayo Clinic staff

Complications of prostatitis can include:

  • Bacterial infection of the blood (bacteremia)
  • Inflammation of the coiled tube attached to the back of the testicle (epididymitis)
  • Pus-filled cavity in the prostate (prostatic abscess)
  • Abnormalities in semen and infertility (this can occur with chronic prostatitis)

Prostatitis, cancer and PSA levels
Prostatitis can cause elevated levels of prostate-specific antigen (PSA), a protein produced by the prostate. PSA testing is generally used to screen for prostate cancer. Cancerous cells produce more PSA than do noncancerous cells, so higher than normal levels of PSA in the blood may indicate prostate cancer. However, conditions other than prostate cancer, including prostatitis, also can increase PSA levels.

There's no direct evidence that prostatitis can lead to prostate cancer.

References
  1. Meyrier A, et al. Acute and chronic bacterial prostatitis. http://www.uptodate.com/home/index.html. Accessed Jan. 21, 2011.
  2. Pontari M. Chronic prostatitis/chronic pelvic pain syndrome. http://www.uptodate.com/home/index.html. Accessed Jan. 22, 2011.
  3. Nickel JC. Inflammatory conditions of the male genitourinary tract: Prostatitis and related conditions, orchitis, and epididymitis. In: Wein AJ, et al. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/117299121-3/794153691/1445/12.html#4-u1.0-B978-0-7216-0798-6..50011-X--cesec1_747. Accessed Jan. 21, 2011.
  4. Murphy AB, et al. Pharmacotherapy strategies in chronic prostatitis/chronic pelvic pain syndrome management. Expert Opinion on Pharmacotherapy. 2010;11:1255.
  5. Ramakrishnan K, et al. Prostatitis: Acute and chronic. Primary Care. 2010;37:547.
  6. Drezner JA, et al. Sports medicine. In: Rakel RE. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/217852368-11/0/1481/488.html?tocnode=53394295&fromURL=488.html#4-u1.0-B978-1-4160-2467-5..50043-9--cesec49_2509. Accessed Sept. 8, 2010.
  7. Castle EC (expert opinion). Mayo Clinic, Scottsdale, Ariz. Feb. 14, 2011.
DS00341 March 18, 2011

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