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Complications

By Mayo Clinic staff

The CPPD crystal deposits that cause pseudogout can also lead to joint damage. Bones in the affected joint or joints can develop cysts, bone spurs and cartilage loss. Further damage can lead to fractures.

Joint damage associated with CPPD crystals sometimes mimics the signs and symptoms of osteoarthritis or rheumatoid arthritis.

References
  1. Pseudogout. American College of Rheumatology. http://www.rheumatology.org/public/factsheets/diseases_and_conditions/pseudogout.asp. Accessed Feb. 15, 2010.
  2. Mercier LR. Pseudogout. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009: 380. http://www.mdconsult.com/das/book/body/182089558-3/949024313/2088/537.html#4-u1.0-B978-0-323-05609-0..00025-3--sc0320_11038. Accessed Feb. 15, 2010.
  3. Gravel JG, et al. Rheumatic diseases. In: Rakel RE. Rakel: Textbook of Family Medicine. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/182089558-3/949024313/1481/505.html#4-u1.0-B978-1-4160-2467-5..50045-2--cesec51_2681. Accessed Feb. 15, 2010.
  4. Becker MA. Clinical manifestations and diagnosis of calcium pyrophosphate crystal deposition disease. http://www.uptodate.com/home/index.html. Accessed Feb. 15, 2010.
  5. Becker MA. Pathogenesis and etiology of calcium pyrophosphate crystal deposition disease. http://www.uptodate.com/home/index.html. Accessed Feb. 15, 2010.
  6. Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) (pseudo gout). The Arthritis Foundation. http://www.arthritis.org/disease-center.php?disease_id=7&df=treatments. Accessed Feb. 15, 2010.
  7. Richette P, et al. An update on the epidemiology of calcium pyrophosphate dihydrate crystal deposition disease. Rheumatology. 2009;48:711.
  8. Chang-Miller A (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 23, 2010.
DS00717 April 2, 2010

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