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Definition
By Mayo Clinic staff
Pseudomembranous colitis is inflammation of the colon that occurs in some people who have taken antibiotics. Pseudomembranous colitis is sometimes called antibiotic-associated colitis or C. difficile colitis. The inflammation in pseudomembranous colitis is almost always associated with an overgrowth of the bacterium Clostridium difficile.
Severe pseudomembranous colitis can be life-threatening. However, treatment is usually successful.
References
- Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Oct. 21, 2012.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Oct. 21, 2012.
- Kelly CP. Current strategies for management of initial Clostridium difficile infection. Journal of Hospital Medicine. 2012;7:S5.
- Ananthakrishnan AN. Clostridium difficile infection: Epidemiology, risk factors and management. Nature Reviews Gastroenterology & Hepatology. 2011;8:17.
- Johnson S. Meeting the challenge of recurrent Clostridium difficile infection. Journal of Hospital Medicine. 2012;7:S11.
- Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniqId=230100505-57. Accessed Oct. 21, 2012.
- Gallegos-Orozco JF, et al. Successful colonoscopic fecal transplant for severe acute Clostridium difficile pseudomembranous colitis. Revista de gastroenterología de México. 2012;77:40.
- Diarrhea. ADA Nutrition Care Manual. http://nutritioncaremanual.org/vault/editor/Docs/DiarrheaNutritionTherapy_FINAL.pdf. Accessed Oct.21, 2012.
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