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    Lawrence E. Gibson, M.D.

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Question

Psoriasis treatment: Can fish oil supplements reduce symptoms?

Can fish oil supplements improve psoriasis symptoms?

Answer

from Lawrence E. Gibson, M.D.

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Illustration showing how psoriasis develops 
How psoriasis develops

A number of studies show that fish oil supplements may reduce inflammation and improve psoriasis symptoms, such as itching and scaling. However, not all studies have shown fish oil supplements to be effective psoriasis treatment, and, as with any supplement, there may be some risks.

Fish oil is a good source of omega-3 fatty acids. Omega-3 fatty acids — eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in particular — play an important role in reducing inflammation. EPA and DHA may also suppress the body's response to white blood cells called T lymphocytes or T cells. If you have psoriasis, overactive T cells trigger immune responses and cause an increased production of both healthy skin cells and more T cells. The skin cells can't slough off quickly enough and accumulate on the skin's surface, creating thick, scaly psoriasis patches.

Fish oil supplements are generally recognized as safe if taken as directed. Side effects are usually mild, but can include a fishy aftertaste, heartburn and nausea. Doses greater than 3 grams a day can affect blood clotting, increase your risk of bleeding and decrease blood pressure. This may be of particular concern if you're taking blood-thinning medication or high blood pressure medication.

If you're considering dietary supplements or other alternative therapies for psoriasis treatment, consult your doctor. He or she can help you weigh the pros and cons of specific alternative therapies, including fish oil supplements.

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References
  1. Smith N, et al. Complementary and alternative medicine for psoriasis: A qualitative review of the clinical trial literature. Journal of the American Academy of Dermatology. 2009;61:841.
  2. Bodemer AA. Psoriasis. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Elsevier Saunders; 2007. http://www.mdconsult.com/das/book/body/172349793-3/0/1494/116.html?tocnode=54115041&fromURL=116.html#4-u1.0-B978-1-4160-2954-0..50073-9_3554. Accessed Nov. 19, 2009.
  3. Fish oil. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Nov. 19, 2009.
  4. Simopoulos AP. Omega-3 fatty acids in inflammation and autoimmune diseases. Journal of the American College of Nutrition. 2002;21:495.
AN02043 Feb. 2, 2010

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