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Risk factors
By Mayo Clinic staffAnyone can develop psoriasis, but these factors can increase your risk of developing the disease:
- Family history. Perhaps the most significant risk factor for psoriasis is having a family history of the disease. About one in three people with psoriasis has a close relative who also has the condition.
- Other medical conditions. People with HIV are more likely to develop psoriasis than people with healthy immune systems are. Children and young adults with recurring infections, particularly strep throat, also may be at increased risk.
- Stress. Because stress can impact your immune system, high stress levels may increase your risk of psoriasis.
- Obesity. Excess weight increases your risk of inverse psoriasis. In addition, plaques associated with all types of psoriasis often develop in skin creases and folds.
- Smoking. Smoking tobacco not only increases your risk of psoriasis but also may increase the severity of the disease. Smoking may also play a role in the initial development of the disease.
References
- Gudjonsson JE, et al. Psoriasis. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/popup.aspx?aID=2983781. Accessed Jan. 26, 2009.
- Psoriasis and psoriatic arthritis. American Academy of Dermatology. http://www.aad.org/public/publications/pamphlets/common_psoriasis.html. Accessed Jan. 26, 2009.
- Bodemer AA. Psoriasis. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/117935134-4/796383039/1494/116.html#4-u1.0-B978-1-4160-2954-0..50073-9_3554. Accessed Jan. 26, 2009.
- Questions and answers about psoriasis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/hi/topics/psoriasis/psoriasis.htm. Accessed Jan. 26, 2009.
- Fluhr JW, et al. Emollients, moisturizers, and keratolytic agents in psoriasis. Clinics in Dermatology. 2008;26:380.
- Feldman SR, et al. Epidemiology, clinical manifestations, and diagnosis of psoriasis. http://www.uptodate.com/home/index.html. Accessed Jan. 26, 2009.
- Feldman SR, et al. Treatment of psoriasis. http://www.uptodate.com/home/index.html. Accessed Jan. 26, 2009.
- Aloe. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Jan. 27, 2009.
- Capsicum. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Jan. 27, 2009.
- Fish oil. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Jan. 28, 2009.
- Traub M, et al. Psoriasis: Pathophysiology, conventional and alternative approaches to treatment. Alternative medicine review. 2007;12:319.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 29, 2009.
- FDA statement on the voluntary withdrawal of Raptiva from the U.S. market. U.S. Food and Drug Administration. http://www.fda.gov/bbs/topics/NEWS/2009/NEW01992.html. Accessed April 9, 2009.
- FDA approves new drug to treat psoriasis. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm183851.htm. Accessed Oct. 27, 2009.
