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Complications

By Mayo Clinic staff

Complications of pulmonary fibrosis may include:

  • High blood pressure in your lungs (pulmonary hypertension). Unlike systemic high blood pressure, this condition affects only the arteries in your lungs. It begins when the smallest arteries and capillaries are compressed by scar tissue, causing increased resistance to blood flow in your lungs. This in turn raises pressure within the pulmonary arteries. Pulmonary hypertension is a serious illness that becomes progressively worse and may eventually prove fatal.
  • Right-sided heart failure (cor pulmonale). This serious condition occurs when your heart's lower right chamber (ventricle) has to pump harder than usual to move blood through partially blocked pulmonary arteries.
  • Respiratory failure. This is often the last stage of chronic lung disease. It occurs when blood-oxygen levels fall dangerously low.
  • Lung cancer. Long-standing pulmonary fibrosis also increases your risk of developing lung cancer.
References
  1. Idiopathic pulmonary fibrosis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/ipf/ipf_all.html. Accessed Jan. 20, 2011.
  2. Rust G. Interstitial lung diseases. In: Rakel RE. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/191205553-4/0/1481/0.html#. Accessed Jan. 20, 2011.
  3. King TE. Approach to the adult with interstitial lung disease: Clinical evaluation. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  4. Blundin M. Idiopathic pulmonary fibrosis. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed Jan. 20, 2011.
  5. King TE. Approach to the adult with interstitial lung disease: Diagnostic testing. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  6. Rosenow EC (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 25, 2011.
  7. King TE. Treatment of idiopathic pulmonary fibrosis. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  8. Pulmonary rehabilitation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/pulreh/pulreh_all.html. Accessed Jan. 20, 2011.
DS00927 March 15, 2011

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