Pulmonary fibrosis

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Risk factors

By Mayo Clinic staff

Factors that make you more susceptible to pulmonary fibrosis include:

  • Age. Although pulmonary fibrosis has been diagnosed in children and infants, the disorder is much more likely to affect middle-aged and older adults.
  • Smoking. Far more smokers and former smokers develop pulmonary fibrosis than do people who have never smoked.
  • Your occupation. You have an increased risk of developing pulmonary fibrosis if you work in mining, farming or construction or if you're exposed to pollutants known to damage your lungs.
  • Cancer treatments. Having radiation treatments to your chest or using certain chemotherapy drugs makes you more susceptible to pulmonary fibrosis.
  • Genetic factors. Some types of pulmonary fibrosis appear to run in families, so a genetic component is suspected.
References
  1. Idiopathic pulmonary fibrosis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/ipf/ipf_all.html. Accessed Jan. 20, 2011.
  2. Rust G. Interstitial lung diseases. In: Rakel RE. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/191205553-4/0/1481/0.html#. Accessed Jan. 20, 2011.
  3. King TE. Approach to the adult with interstitial lung disease: Clinical evaluation. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  4. Blundin M. Idiopathic pulmonary fibrosis. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed Jan. 20, 2011.
  5. King TE. Approach to the adult with interstitial lung disease: Diagnostic testing. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  6. Rosenow EC (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 25, 2011.
  7. King TE. Treatment of idiopathic pulmonary fibrosis. http://www.uptodate.com/home/index.html. Accessed Jan. 20, 2011.
  8. Pulmonary rehabilitation. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/pulreh/pulreh_all.html. Accessed Jan. 20, 2011.
DS00927 March 15, 2011

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