Pyloric stenosis

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Risk factors

By Mayo Clinic staff

Risk factors for pyloric stenosis include:

  • Sex. Pyloric stenosis occurs more often in males than in females.
  • Birth order. About one-third of babies affected by pyloric stenosis are firstborns.
  • Family history. More than 1 in 10 babies with pyloric stenosis has a family member who had the disorder.
  • Early antibiotic use. Babies given certain antibiotics, such as erythromycin, in the first weeks of life for whooping cough (pertussis) have an increased risk of pyloric stenosis. In addition, babies born to mothers who were given certain antibiotics in late pregnancy also may have an increased risk of pyloric stenosis.
References
  1. Olive AP, et al. Infantile hypertrophic pyloric stenosis. http://www.uptodate.com/home/index.html. Accessed June 23, 2010.
  2. Sondheimer JM, et al. Gastrointestinal tract. In: Hay WW Jr., et al. Current Diagnosis & Treatment: Pediatrics. 19th ed. New York, N.Y.: McGraw-Hill; 2007. http://www.accessmedicine.com/content.aspx?aID=3403837. Accessed June 23, 2010.
  3. D'Agostino J. Common abdominal emergencies in children. Emergency Medicine Clinics of North America. 2002;20:139.
  4. Guidelines for surgical treatment of infantile hypertrophic pyloric stenosis. Los Angeles, Ca.: International Pediatric Endosurgery Group. http://www.ipeg.org/education/guidelines/pyloric.html. Accessed July 7, 2010.
  5. Pyloric stenosis. The American Pediatric Surgical Association. http://www.eapsa.org//Surgeons/Content/NavigationMenu/Media/Resources/Pyloric_Stenosis.htm. Accessed July 7, 2010.
  6. Hoecker J (expert opinion). Mayo Clinic, Rochester, Minn. July 8, 2010.
DS00815 Aug. 21, 2010

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