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Definition
By Mayo Clinic staffPyoderma gangrenosum is a condition that causes large, painful sores (ulcers) to develop on your skin, most often on your legs.
It's not certain what causes pyoderma gangrenosum, but it may be related to a disorder of the immune system. About half the people with pyoderma gangrenosum have an underlying chronic health condition.
Pyoderma gangrenosum is rare. Effective treatment for pyoderma gangrenosum is available, but in some cases, the ulcers may leave scars. Early diagnosis and therapy reduces your risk of scarring. Occasionally, pyoderma gangrenosum may return.
Symptoms
