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Causes
By Mayo Clinic staffThe cause of pyoderma gangrenosum isn't well understood. It's often associated with inflammatory conditions, such as ulcerative colitis and Crohn's disease. If you have pyoderma gangrenosum, new skin trauma, such as a cut or puncture wound, may result in the formation of new ulcers. This tendency of new ulcers to form from trauma, including surgery, is known as pathergy.
- Pyoderma gangrenosum. The Merck Manuals Online: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec10/ch117/ch117h.html. Accessed April 21, 2010.
- Peppercorn MA. Skin and eye manifestations of inflammatory bowel disease. http://www.uptodate.com/home/index.html. Accessed April 8, 2010.
- Habif TP. Hypersensitivity syndromes and vasculitis. In: Habif TP. Clinical Dermatology. 5th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7234-3541-9..00027-4--s0815&uniq=196584586&isbn=978-0-7234-3541-9&sid=986856689. Accessed April 21, 2010.
- Cohen PR. Neutrophilic dermatoses: A review of current treatment options. American Journal of Clinical Dermatology. 2009:10:301.
- Moschella SL. Neutrophilic dermatoses. http://www.uptodate.com/home/index.html. Accessed April 21, 2010.
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