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Risk factors
By Mayo Clinic staffPyoderma gangrenosum is most common in people in their 40s and 50s, but can occur at any age. It's also associated with inflammatory conditions, including:
- Ulcerative colitis. This disease of the large intestine causes chronic inflammation of your large intestine.
- Crohn's disease. Like ulcerative colitis, Crohn's disease causes long-term inflammation that can occur anywhere along your digestive tract.
- Rheumatoid arthritis. Rheumatoid arthritis refers to a condition in which the thin membranes surrounding your joints become irritated and inflamed.
- Hepatitis. This condition causes your liver to become inflamed. The cause of hepatitis may be a virus or a disorder of your immune system.
References
- Pyoderma gangrenosum. The Merck Manuals Online: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec10/ch117/ch117h.html. Accessed April 21, 2010.
- Peppercorn MA. Skin and eye manifestations of inflammatory bowel disease. http://www.uptodate.com/home/index.html. Accessed April 8, 2010.
- Habif TP. Hypersensitivity syndromes and vasculitis. In: Habif TP. Clinical Dermatology. 5th ed. Philadelphia, Pa.: Mosby; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7234-3541-9..00027-4--s0815&uniq=196584586&isbn=978-0-7234-3541-9&sid=986856689. Accessed April 21, 2010.
- Cohen PR. Neutrophilic dermatoses: A review of current treatment options. American Journal of Clinical Dermatology. 2009:10:301.
- Moschella SL. Neutrophilic dermatoses. http://www.uptodate.com/home/index.html. Accessed April 21, 2010.
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