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Risk factors
By Mayo Clinic staffPyoderma gangrenosum is most common in people in their 40s and 50s but can occur at any age. It's also associated with the following conditions:
- Ulcerative colitis. This disease of the large intestine causes chronic inflammation of your large intestine.
- Crohn's disease. Like ulcerative colitis, Crohn's disease causes long-term inflammation in the intestine but can occur anywhere along your digestive tract.
- Rheumatoid arthritis. Rheumatoid arthritis refers to a condition in which the thin membranes surrounding your joints become irritated and inflamed.
- Hepatitis. This condition causes your liver to become inflamed. The cause of hepatitis may be a virus or a disorder of your immune system.
