Mayo Clinic Health Manager
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By Mayo Clinic staffSigns and symptoms of pyoderma gangrenosum include:
- Initially, one or more small, red bumps on your skin that resemble spider bites
- Painful, open sores (ulcers) with reddish-purple borders
- Achy joints or pain in your bones
- Tiredness
The ulcers usually appear on your legs but may develop anywhere on your body. If you have several ulcers, they may grow and merge into one larger ulcer.