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Tests and diagnosis
By Mayo Clinic staffThe sudden appearance of unexplainable ulcers on your skin is the first indication that you may have pyoderma gangrenosum. You'll likely have a complete physical exam, including blood tests and other tests, to determine whether you have an underlying health condition that's associated with pyoderma gangrenosum.
A skin biopsy may be necessary to confirm the diagnosis or to rule out another cause. In this test, your doctor removes a small sample of the affected skin. The skin sample is examined under a microscope to confirm a diagnosis of pyoderma gangrenosum.
