What you can expect
By Mayo Clinic staffDuring the quad screen, a member of your health care team takes a sample of blood by inserting a needle into a vein in your arm. The blood sample is sent to a lab for analysis. You can return to your usual activities immediately.
Test results are typically available within a week.
- Canick JA, et al. Second trimester maternal serum screening for Down syndrome. http://www.uptodate.com/index. Accessed Aug. 27, 2012.
- Canick JA, et al. Laboratory issues related to maternal serum screening for Down syndrome. http://www.uptodate.com/index. Accessed Aug. 27, 2012.
- Canick JA, et al. First trimester and integrated screening for Down syndrome and trisomy 18. http://www.uptodate.com/index. Accessed Aug. 27, 2012.
- NINDS anencephaly information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/anencephaly/anencephaly.htm. Accessed Aug. 27, 2012.
- NINDS spina bifida information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/spina_bifida/spina_bifida.htm. Accessed Aug. 27, 2012.
- Ostermaier KK. Management of Down syndrome. http://www.uptodate.com/index. Accessed Aug. 27, 2012.
- Routine tests in pregnancy. American College of Obstetricians and Gynecologists. http://www.acog.org/~/media/For%20Patients/faq133.pdf?dmc=1&ts=20120827T1517335564. Accessed Aug. 27, 2012.
- Bianchi DW, et al. Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencing. Obstetrics & Gynecology. 2012;119:890.
- Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 28, 2012.


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