Rabies

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Causes

By Mayo Clinic staff

Rabies infection is caused by the rabies virus. The virus is spread through the saliva of infected animals. Infected animals can spread the virus by biting another animal or a person. In rare cases, rabies can be spread when infected saliva gets into an open wound or the mucous membranes, such as the mouth or eyes. This could occur if an infected animal were to lick an open cut on your skin.

Animals that can transmit the rabies virus
Any mammal can transmit the rabies virus. The animals most likely to transmit the rabies virus to people include:

Pets and farm animals

  • Cats
  • Cows
  • Dogs
  • Ferrets
  • Goats
  • Horses
  • Rabbits

Wild animals

  • Bats
  • Beavers
  • Coyotes
  • Foxes
  • Monkeys
  • Raccoons
  • Skunks
  • Woodchucks

There has never been a documented case of human-to-human rabies transmission. In rare cases, the virus has been transmitted to tissue and organ transplant recipients from an infected organ.

Risk factors Symptoms
References
  1. Rabies basics. Centers for Disease Control and Prevention. http://www.cdc.gov/rabies/exposure/index.html. Accessed Nov. 23, 2010.
  2. Rupprecht CE. Clinical manifestations, diagnosis, and treatment of rabies. http://www.uptodate.com/home/index.html. Accessed Nov. 23, 2010.
  3. Fort GG, et al. Rabies. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?sid=1095900802&eid=4-u1.0-B978-0-323-05610-6..00027-5--sc0010&isbn=978-0-323-05610-6&type=bookPage&sectionEid=4-u1.0-B978-0-323-05610-6..00027-5--sc0010&uniqId=230129353-3. Accessed Nov. 23, 2010.
  4. Bassin SL, et al. Rhabdoviruses. In: Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 76th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-443-06839-3..00163-6&isbn=978-0-443-06839-3&type=bookPage&sectionEid=4-u1.0-B978-0-443-06839-3..00163-6&uniqId=227823193-5#4-u1.0-B978-0-443-06839-3..00163-6. Accessed Nov. 23, 2010.
  5. Harper MB. Infection following bites. In: Long SS, et al., eds. Long: Principles and Practice of Pediatric Infectious Diseases. 3rd ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/227823193-4/1087364479/1679/96.html#4-u1.0-B978-0-443-06687-0..50095-3--cesec28_1889. Accessed Nov. 23, 2010.
  6. DeMaria A, et al. Rabies immune globulin and vaccine. http://www.uptodate.com/home/index.html. Accessed Nov. 23, 2010.
  7. Jackson AC. Rabies. Neurologic Clinics. 2008;26:717.
  8. Steckelberg JM (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 7, 2010.
DS00484 Jan. 28, 2011

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