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Tests and diagnosis
By Mayo Clinic staffWhen a person has experienced known or probable exposure to a high dose of radiation from an accident or attack, medical personnel take a number of steps to determine the absorbed radiation dose. This information is essential for determining how severe the illness is likely to be, which treatments to use and whether a person is likely to survive.
Information important for determining an absorbed dose includes:
- Known exposure. Details about distance from the source of radiation and duration of exposure can help provide a rough estimate of the severity of radiation sickness.
- Vomiting and other symptoms. The time between radiation exposure and the onset of vomiting is a fairly accurate screening tool to estimate absorbed radiation dose. The shorter the time before the onset of this sign, the higher the dose is. The severity and timing of other signs and symptoms may also help medical personnel determine the absorbed dose.
- Blood tests. Frequent blood tests over several days enable medical personnel to look for drops in disease-fighting white blood cells and abnormal changes in the DNA of blood cells. These factors indicate the degree of bone marrow damage, which is determined by the level of an absorbed dose.
- Dosimeter. A device called a dosimeter can measure the absorbed dose of radiation but only if it was exposed to the same radiation event as the affected person.
- Survey meter. A device such as a Geiger counter can be used to survey people to determine the body location of radioactive particles.
- Type of radiation. A part of the larger emergency response to a radioactive accident or attack would include identifying the type of radiation people have been exposed to. This information would guide some decisions for treating people with radiation sickness.
- Upton AC. Radiation injury. In: Goldman L, et al., eds. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/190749348-4/972374138/1492/93.html#4-u1.0-B978-1-4160-2805-5..50023-9--cesec10_713. Accessed March 23, 2010.
- Colwell CB, et al. Radiation injuries. In: Marx JA, et al., eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo.: Mosby; 2006. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..00144-4&uniq=190749348&isbn=978-0-323-05472-0&sid=972411702. Accessed March 23, 2010.
- Siegel D. Preparation for terrorist threats: Radiation injury. Clinical Pediatric Emergency Medicine. 2009;10:136.
- Bushberg JT. Radiation exposure and contamination. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://merck.com/mmpe/sec21/ch317/ch317a.html#CHDCIEIA. Accessed March 23, 2010.
- Ferri FF, et al. Radiation exposure. In: Ferri FF. Ferri's Clinical Advisor 2010. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/das/book/body/190749348-10/972432685/2088/550.html#4-u1.0-B978-0-323-05609-0..00027-7--s0170_11313. Accessed March 23, 2010.
- Vetter RJ (expert opinion). Mayo Clinic, Rochester, Minn. April 3, 2010.
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