Raynaud's disease

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Risk factors

By Mayo Clinic staff

Risk factors for primary Raynaud's include:

  • Your gender. Primary Raynaud's affects women more than men.
  • Your age. Although anyone can develop the condition, primary Raynaud's often begins between the ages of 15 and 30.
  • Where you live. The disorder is also more common in people who live in colder climates.
  • Your family history. Additionally, a family history appears to increase your risk of primary Raynaud's. About one-third of people with primary Raynaud's have a first-degree relative — a parent, sibling or child — with the disorder.

Risk factors for secondary Raynaud's include:

  • Associated diseases. These include conditions such as scleroderma and lupus.
  • Certain occupations. People in occupations that cause repetitive trauma, such as workers who operate tools that vibrate, also may be more vulnerable to secondary Raynaud's.
  • Exposure to certain substances. Smoking, medications that affect the blood vessels and exposure to chemicals such as vinyl chloride are associated with an increased risk of Raynaud's.
References
  1. Questions and answers about Raynaud's phenomenon. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Raynauds_Phenomenon/default.asp. Accessed Aug. 2, 2011.
  2. Raynaud's disease. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/raynaud/ray_all.html. Accessed Aug. 2, 2011.
  3. Wigley FM. Nonpharmacologic therapy for the Raynaud phenomenon. http://www.uptodate.com/home/index.html. Accessed Aug. 2, 2011.
  4. Wigley FM. Pharmacologic and surgical treatment of the Raynaud phenomenon. http://www.uptodate.com/home/index.html. Accessed Aug. 2, 2011.
  5. Sayeed SM, et al. Raynaud's phenomenon. In: Ferri FF. Ferri's Clinical Advisor 2012. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8&isbn=978-0-323-05611-3&uniqId=270492172-3#4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP. Accessed Aug. 2, 2011.
  6. Natural product effectiveness checker results: Raynaud's syndrome. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Aug. 9, 2011.
DS00433 Oct. 20, 2011

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