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Risk factors

By Mayo Clinic staff

Factors that may increase the risk of rheumatic fever include:

  • Family history. Some people may carry a gene or genes that make them more likely to develop rheumatic fever.
  • Type of strep bacteria. Certain strains of strep bacteria are more likely to contribute to rheumatic fever than are other strains.
  • Environmental factors. A greater risk of rheumatic fever is associated with overcrowding, poor sanitation, and other conditions that may easily result in the rapid transmission or multiple exposures to strep bacteria.
References
  1. Fort GG. Rheumatic fever. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05610-6..00027-5--sc0105&isbn=978-0-323-05610-6&type=bookPage&sectionEid=4-u1.0-B978-0-323-05610-6..00027-5--sc0105&uniqId=224600605-3. Accessed Oct. 28, 2010.
  2. Rheumatic fever. In: Marx JA, et al., eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. St. Louis, Mo.: Mosby; 2009. http://www.mdconsult.com/books/page.do?sid=1075999583&eid=4-u1.0-B978-0-323-05472-0..00081-5--s0050&isbn=978-0-323-05472-0&type=bookPage&sectionEid=4-u1.0-B978-0-323-05472-0..00081-5--s0050&uniqId=224600605-4. Accessed Oct. 28, 2010.
  3. Rheumatic fever. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec19/ch281/ch281a.html. Accessed Oct. 28, 2010.
  4. Choby B. Diagnosis and treatment of streptococcal pharyngitis. American Family Physician. 2009;79:383.
  5. Gibofsky A, et al. Epidemiology and pathogenesis of acute rheumatic fever. http://www.uptodate.com/home/index.html. Accessed Oct. 28, 2010.
  6. Gibofsky A, et al. Treatment and prevention of rheumatic fever. http://www.uptodate.com/home/index.html. Accessed Oct. 28, 2010.
  7. Report for the second meeting of World Health Organization's subcommittee of the Expert Committee of the Selection and Use of Essential Medicines: Antibiotic use for the prevention and treatment of rheumatic fever and rheumatic heart disease in children. Geneva, Switzerland: Royal Hobart Hospital and University of Tasmania. http://www.who.int/selection_medicines/committees/subcommittee/2/RheumaticFever_review.pdf. Accessed Oct. 28, 2010. Hoecker JL (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 3, 2010.
DS00250 Jan. 21, 2011

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