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Definition
By Mayo Clinic staff
Rheumatoid arthritis is a chronic inflammatory disorder that typically affects the small joints in your hands and feet. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of your joints, causing a painful swelling that can eventually result in bone erosion and joint deformity.
An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body's tissues. In addition to causing joint problems, rheumatoid arthritis sometimes can affect other organs of the body — such as the skin, eyes, lungs and blood vessels.
Although rheumatoid arthritis can occur at any age, it usually begins after age 40. The disorder is much more common in women than in men. Treatment focuses on controlling symptoms and preventing joint damage.
- Handout on health: Rheumatoid arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Rheumatic_Disease/default.asp. Accessed June 26, 2013.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.mdconsult.com/books/about.do?about=true&eid=$eid&isbn=978-1-4557-0295-4&uniqId=398813857-1936. Accessed June 26, 2013.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed June 26, 2013.
- Frontera WR, et al. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-6/0/1678/0.html. Accessed June 26, 2013.
- Venables PJ, et al. Diagnosis and differential diagnosis of rheumatoid arthritis. http://www.uptodate.com/home. Accessed June 26, 2013.
- Schur PH, et al. General principles of management of rheumatoid arthritis in adults. http://www.uptodate.com/home. Accessed June 26, 2013.
- Matteson EL (expert opinion). Mayo Clinic, Rochester, Minn. July 2, 2013.
- Schur PH, et al. Nonpharmacologic and preventive therapies of rheumatoid arthritis. http://www.uptodate.com/home. Accessed June 26, 2013.
- Rheumatoid arthritis and complementary health approaches. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/RA/getthefacts.htm. Accessed July 1, 2013.
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