Tests and diagnosisBy Mayo Clinic staff
Rheumatoid arthritis can be difficult to diagnose in its early stages because the early signs and symptoms mimic those of many other diseases. There is no one blood test or physical finding to confirm the diagnosis.
During the physical exam, your doctor will check your joints for swelling, redness and warmth. He or she will also check your reflexes and muscle strength.
People with rheumatoid arthritis tend to have an elevated erythrocyte sedimentation rate (ESR, or sed rate), which indicates the presence of an inflammatory process in the body. Other common blood tests look for rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies.
Your doctor may recommend X-rays to help track the progression of rheumatoid arthritis in your joints over time.
- Handout on health: Rheumatoid arthritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Rheumatic_Disease/default.asp. Accessed June 26, 2013.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.mdconsult.com/books/about.do?about=true&eid=$eid&isbn=978-1-4557-0295-4&uniqId=398813857-1936. Accessed June 26, 2013.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed June 26, 2013.
- Frontera WR, et al. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-6/0/1678/0.html. Accessed June 26, 2013.
- Venables PJ, et al. Diagnosis and differential diagnosis of rheumatoid arthritis. http://www.uptodate.com/home. Accessed June 26, 2013.
- Schur PH, et al. General principles of management of rheumatoid arthritis in adults. http://www.uptodate.com/home. Accessed June 26, 2013.
- Matteson EL (expert opinion). Mayo Clinic, Rochester, Minn. July 2, 2013.
- Schur PH, et al. Nonpharmacologic and preventive therapies of rheumatoid arthritis. http://www.uptodate.com/home. Accessed June 26, 2013.
- Rheumatoid arthritis and complementary health approaches. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/RA/getthefacts.htm. Accessed July 1, 2013.