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By Mayo Clinic staffMost children recover fully from roseola within a week of the onset of the fever. With your doctor's advice, you can give your child over-the-counter medications to reduce fever, such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin, others). However, don't give aspirin to a child who has a viral illness because aspirin has been associated with the development of Reye's syndrome, which can be serious.
There's no specific treatment for roseola, although some doctors may prescribe the antiviral medication ganciclovir (Cytovene) to treat the infection in people with weakened immunity. Antibiotics aren't effective in treating viral illnesses, such as roseola.