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Causes

By Mayo Clinic staff

A spleen may rupture due to:

  • Injury to the left side of the body. A ruptured spleen is typically caused by a blow to the left upper abdomen or the left lower chest, such as might happen during sporting mishaps, fistfights and car crashes. An injured spleen may rupture soon after the abdominal trauma or, in some cases, days or even weeks after the injury.
  • An enlarged spleen. Your spleen can become enlarged when blood cells accumulate in the spleen. An enlarged spleen can be caused by various underlying problems, such as mononucleosis and other infections, liver disease, and blood cancers.
References
  1. Hoffman R, et al. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniqId=230100505-56. Accessed Jan. 10, 2013.
  2. Gannon EH, et al. Splenic injuries in athletes: A review. Current Sports Medicine Reports. 2010;9:111.
  3. DiSabatino A, et al. Post-splenectomy and hypo-splenic states. The Lancet. 2011;378:26.
  4. Townsend CM, et al. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/208746819-6/0/1565/0.html. Accessed Jan. 12, 2013.
  5. Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Jan. 12, 2013.
  6. AskMayoExpert. What should be done before splenectomy? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
DS00872 April 10, 2013

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