PreventionBy Mayo Clinic staff
If you've been diagnosed with an enlarged spleen, ask your doctor whether you should avoid activities that could cause a ruptured spleen. For instance, people with mononucleosis — a viral infection that can cause an enlarged spleen — may be asked to avoid contact sports and other activities that increase the risk of abdominal trauma for several weeks. Protecting the spleen from bumps and blows may reduce the risk of a ruptured spleen.
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