Schizoaffective disorder

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Risk factors

By Mayo Clinic staff

Schizoaffective disorder is thought to involve delays or variations in the way a child's brain develops — like in schizophrenia. Genetics plays a role in development of the disorder, and people with relatives who have schizoaffective disorder are more likely to develop this condition. Environmental factors also may be involved.

Factors that increase the risk of developing the schizoaffective disorder include:

  • Having a relative who has schizophrenia
  • Having a relative who has a mood disorder
  • Having a relative who has schizoaffective disorder
References
  1. Schizoaffective disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Oct. 14, 2010.
  2. Schizophrenia. In: Hales RE, et al. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Washington, D.C.: American Psychiatric Pub; 2008. http://www.psychiatryonline.com. Accessed Oct. 14, 2010.
  3. Factsheet: Schizoaffective disorder. Mental Health America. http://www.mentalhealthamerica.net/index.cfm?objectid=C7DF97FD-1372-4D20-C8F0FBF1C871E040. Accessed Oct. 14, 2010.
  4. Schizoaffective disorder. National Alliance on Mental Illness. http://www.nami.org/Content/ContentGroups/Helpline1/Schizoaffective_Disorder.htm. Accessed Oct. 14, 2010.
  5. Gejman PV, et al. The role of genetics in the etiology of schizophrenia. Psychiatric Clinics of North America. 2010;33:35.
  6. Jibson MD. Schizophrenia: Clinical presentation, epidemiology, and pathophysiology. http://www.uptodate.com/home/index.html. Accessed Oct. 14, 2010.
  7. Jibson MD. Schizophrenia: Diagnostic evaluation and treatment. http://www.uptodate.com/home/index.html. Accessed Oct. 14, 2010.
  8. Schizoaffective disorder. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec15/ch202/ch202d.html. Accessed Oct. 14, 2010.
  9. Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 30, 2010.
  10. Schizoaffective. Micromedex Healthcare Series. http://www.micromedex.com. Accessed Dec. 2, 2010.
DS00866 Dec. 21, 2010

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