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Definition

By Mayo Clinic staff

Schizophrenia is a group of severe brain disorders in which people interpret reality abnormally. Schizophrenia may result in some combination of hallucinations, delusions, and disordered thinking and behavior.

Contrary to some popular belief, schizophrenia isn't split personality or multiple personality. The word "schizophrenia" does mean "split mind," but it refers to a disruption of the usual balance of emotions and thinking.

Schizophrenia is a chronic condition, requiring lifelong treatment.

Symptoms
References
  1. Schizophrenia and other psychotic disorders. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Nov. 26, 2011.
  2. Minzenberg MJ, et al. Schizophrenia. In: Hales RE, et al. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Washington, D.C.: American Psychiatric Publishing; 2008. http://www.psychiatryonline.com/resourceToc.aspx?resourceID=5. Accessed Nov. 26, 2011.
  3. Schizophrenia. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed Nov. 26, 2011.
  4. Fischer BA, et al. Schizophrenia: Clinical manifestations, course, assessment, and diagnosis. http://www.uptodate.com/home/index.html. Accessed Nov. 26, 2011.
  5. Jibson MD. Schizophrenia: Epidemiology and pathogenesis. http://www.uptodate.com/home/index.html. Accessed Nov. 26, 2011.
  6. Stroup TS, et al. Pharmacotherapy for schizophrenia: Acute and maintenance phase treatment. http://www.uptodate.com/home/index.html. Accessed Nov. 26, 2011.
  7. Aripiprazole. U.S. National Library of Medicine. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000221/. Accessed Nov. 26, 2011.
  8. Risperidone. U.S. National Library of Medicine. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000944/. Accessed Nov. 26, 2011.
  9. Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 30, 2011.
  10. Wall CA (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 20, 2011.
DS00196 Jan. 27, 2012

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