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Symptoms
By Mayo Clinic staff
Scleroderma symptoms vary, depending on which organ systems are involved. Diagnosis can be difficult because some of the early symptoms are common in the general population, and aren't always associated with scleroderma. The most prevalent signs and symptoms of scleroderma include:
- Raynaud's phenomenon. An exaggerated response to cold temperatures or emotional distress, this condition constricts the small blood vessels in the hands and feet and causes numbness, pain or color changes in the fingers or toes.
- Gastroesophageal reflux disease (GERD). In addition to acid reflux, which can damage the section of esophagus nearest your stomach, you may also have problems absorbing nutrients if your intestinal muscles aren't moving food properly through your intestines.
- Skin changes. These changes may include swollen fingers and hands; thickened patches of skin, particularly on the fingers; and tight skin around the hands, face or mouth. Skin can appear shiny because it's so tight, and movement of the affected area may be restricted.
Localized scleroderma
The two main varieties of localized scleroderma, which affects only the skin, are distinguished by very distinctive signs and symptoms:
- Morphea. This variety features oval-shaped thickened patches of skin that are white in the middle, with a purple border.
- Linear scleroderma. This variety, which is more common in children, features bands or streaks of hardened skin on one or both arms or legs, or on the forehead.
Systemic scleroderma
This type of scleroderma, also called systemic sclerosis, affects not only your skin but also your blood vessels and internal organs. Subcategories are defined by what portions of your body are affected. One variation is known as limited scleroderma, or CREST syndrome.
- Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp. Accessed Aug. 4, 2008.
- Hummers LK, et al. Scleroderma. In: Imboden JB, et al. Current Rheumatology Diagnosis and Treatment. 2nd ed. New York, N.Y.: McGraw-Hill Companies Inc.; 2007. http://www.accessmedicine.com/content.aspx?aid=2725959. Accessed Aug. 4, 2008.
- Denton CP. Classification of scleroderma disorders. http://www.uptodate.com/index.html. Accessed Aug. 4, 2008.
- Varga J. Risk factors for and possible causes of systemic sclerosis (scleroderma). http://www.uptodate.com/index.html. Accessed Aug. 6, 2008.
- Varga J. Overview of the clinical manifestations of systemic sclerosis (scleroderma) in adults. http://www.uptodate.com/index.html. Accessed Aug. 6, 2008.
- What is a rheumatologist? American College of Rheumatology. http://www.rheumatology.org/public/rheumatologist.asp?aud=pat. Accessed Aug. 6, 2008.
