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Treatments and drugs
By Mayo Clinic staffScleroderma has no known cure — no drug will stop the overproduction of collagen. But the localized variety of scleroderma sometimes resolves on its own. And a variety of medications can help control the symptoms of scleroderma or help prevent complications.
Medications
- Dilating the blood vessels. Blood pressure medications that dilate blood vessels may help prevent lung and kidney problems and may help treat Raynaud's disease.
- Suppressing the immune system. Drugs that suppress the immune system, such as those taken after organ transplants, may help reduce scleroderma symptoms.
Therapy
- Physical or occupational therapy. Therapists can help you to manage pain, improve your strength and mobility, and work on performing essential daily tasks to maintain your independence.
- Cosmetic procedures. The appearance of skin lesions associated with scleroderma may be helped by exposure to ultraviolet light. Laser surgery also may help camouflage or eliminate these lesions.
Surgery
- Amputation. If finger ulcers caused by severe Raynaud's disease have developed gangrene, amputation may be necessary.
- Lung transplants. People who have developed high blood pressure in the arteries to their lungs (pulmonary hypertension) may be candidates for lung transplants.
References
- Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp. Accessed Aug. 31, 2010.
- Hummers LK, et al. Scleroderma. In: Imboden JB, et al. Current Rheumatology Diagnosis & Treatment. 2nd ed. New York, N.Y.: McGraw-Hill Medical; 2007. http://www.accessmedicine.com/content.aspx?aid=2725959. Accessed Aug. 31, 2010.
- Denton CP. Classification of scleroderma disorders. http://www.uptodate.com/home/index.html. Accessed Sept. 1, 2010.
- Varga J. Risk factors and possible causes of systemic sclerosis (scleroderma). http://www.uptodate.com/home/index.html. Accessed Sept. 1, 2010.
- Varga J. Overview of the clinical manifestations of systemic sclerosis (scleroderma) in adults. http://www.uptodate.com/home/index.html. Accessed Sept. 1, 2010.
- What is a rheumatologist? American College of Rheumatology. http://www.rheumatology.org/practice/clinical/patients/rheumatologist.asp. Accessed Sept. 1, 2010.
- Varga J, et al. Systemic scleroderma and the scleroderma-spectrum disorders. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: W.B. Saunders Company; 2008. http://www.mdconsult.com/das/book/body/217753976-2/0/1807/575.html?tocnode=55733367&fromURL=575.html#4-u1.0-B978-1-4160-3285-4..10077-4_2830. Accessed Sept. 1, 2010.
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