Risk factors
By Mayo Clinic staffFactors that increase the risk of a scrotal mass vary because of the variety of causes of abnormalities in the scrotum. Significant risk factors include the following:
Undescended or retractile testicle
An undescended testicle is a testicle that never leaves the abdomen and, therefore, never enters the scrotum during fetal development or early infancy. A retractile testicle is one that has descended into the scrotum at some point but retreats to the abdomen. An undescended or retractile testicle may be linked to an increased risk of:
- Inguinal hernia
- Testicular torsion
- Testicular cancer
Abnormalities present at birth
Abnormalities of the testicles, penis or kidneys present at birth (congenital) may increase the risk of a scrotal mass and testicular cancer later in life.
History of testicular cancer
If you have had cancer in one testicle, you're at increased risk of cancer affecting the other testicle. If your father or brother has had testicular cancer, you also have an increased risk of the cancer.
- Montgomery JS, et al. The diagnosis and management of scrotal masses. Medical Clinics of North America. 2011;95:235.
- Wampler SM, et al. Common scrotal and testicular problems. Primary Care: Clinics in Office Practice. 2010;37:613.
- Tiemstra JD, et al. Evaluation of scrotal masses. American Family Physician. 2008;78:1165.
- Trojian TH, et al. Epididymitis and orchitis: An overview. American Family Physician. 2009;79:583.
- Hagerty JA, et al. Pediatric scrotal masses. Clinical Pediatric Emergency Medicine. 2009;10:50.
- Testicular self-exam. American Cancer Society. http://www.cancer.org/cancer/testicularcancer/moreinformation/doihavetesticularcancer/do-i-have-testicular-cancer-self-exam. Accessed May 10, 2011.


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