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Definition
By Mayo Clinic staffSed rate, or erythrocyte sedimentation rate (ESR), is a blood test that can reveal inflammatory activity in your body. A sed rate test isn't a stand-alone diagnostic tool, but it may help your doctor diagnose or monitor the progress of an inflammatory disease.
When your blood is placed in a tall, thin tube, red blood cells (erythrocytes) gradually settle to the bottom. Inflammation can cause the cells to clump together. Because these clumps of cells are denser than individual cells, they settle to the bottom more quickly.
The sed rate test measures the distance red blood cells fall in a test tube in one hour. The farther the red blood cells have descended, the greater the inflammatory response of your immune system.
- Vajpayee N, et al. Hematology principles and procedures: Erythrocyte sedimentation rate. In: McPherson RA, et al. Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. Philadelphia, Pa.: W.B. Saunders Co.; 2006. http://www.mdconsult.com/das/book/body/216253686-3/1043810485/1393/191.html#4-u1.0-B1-4160-0287-1..50033-1--cesec81_1878. Accessed Aug. 25, 2010.
- Warner EA, et al. Common laboratory tests. In: Rakel RA. Textbook of Family Medicine. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/216253686-3/1043810485/1481/690.html#4-u1.0-B978-1-4160-2467-5..50068-3--cesec27_4380. Accessed Aug. 25, 2010.
- ESR. Lab Tests Online. American Association for Clinical Chemistry. http://www.labtestsonline.org/understanding/analytes/esr/multiprint.html. Accessed Aug. 25, 2010.
- Laboratory reference values. Sedimentation. Rochester, Minn.: Mayo Foundation for Medical Education and Research; August 2010.
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