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Causes

By Mayo Clinic staff

Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox. Anyone who's had chickenpox may develop shingles. After you recover from chickenpox, the virus can enter your nervous system and lie hidden for years. Eventually, it may reactivate and travel along nerve pathways to your skin — producing shingles.

The reason for the encore is unclear. But it may be due to lowered immunity to infections as you grow older. Shingles is more common in older adults and in people who have weak immune systems.

Varicella-zoster is part of a group of viruses called herpes viruses, which includes the viruses that cause cold sores and genital herpes. Because of this, shingles is also known as herpes zoster. But the virus that causes chickenpox and shingles is not the same virus responsible for cold sores or genital herpes, a sexually transmitted disease.

Are you contagious?
A person with shingles can pass the varicella-zoster virus to anyone who hasn't had chickenpox. This usually occurs through direct contact with the open sores of the shingles rash. Once infected, the person will develop chickenpox, however, not shingles.

Chickenpox can be dangerous for some groups of people. Until your shingles blisters scab over, you are contagious and should avoid physical contact with:

  • Anyone who has a weak immune system
  • Newborns
  • Pregnant women

References
  1. Shingles: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/shingles/detail_shingles.htm. Accessed June 17, 2009.
  2. Ferri FF. Herpes zoster. In: Ferri's Clinical Advisor 2009. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/143941389-3/853489074/1701/269.html#4-u1.0-B978-0-323-04134-8..50011-2--subchapter24_5768. Accessed June 17, 2009.
  3. Shingles disease: Questions and answers (herpes zoster). Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vpd-vac/shingles/dis-faqs.htm. Accessed June 17, 2009.
  4. Albrecht MA. Epidemiology and pathogenesis of varicella-zoster virus infection: Herpes zoster. http://uptodate.com/home/index/html. Accessed June 18, 2009.
  5. AgePage: Shingles. National Institute on Aging. http://www.niapublications.org/agepages/shingles.asp. Accessed June 18, 2009.
  6. Varicella (chickenpox) vaccine Q&A. Centers for Disease and Prevention. http://www.cdc.gov/vaccines/vpd-vac/varicella/vac-faqs-gen.htm. Accessed June 18, 2009.
  7. Herpes zoster vaccine Q&A (Shingles). Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vpd-vac/shingles/vac-faqs.htm. Accessed June 18, 2009.

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Sept. 4, 2009

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