Definition
By Mayo Clinic staffA skin biopsy removes cells or skin samples from the surface of your body. The sample taken from a skin biopsy is examined to provide information about your medical condition. A doctor uses a skin biopsy to diagnose or rule out certain skin conditions and diseases.
Three main types of skin biopsies are:
- Shave biopsy. A doctor uses a tool similar to a razor to remove a small section of the top layers of skin (epidermis and a portion of the dermis).
- Punch biopsy. A doctor uses a circular tool to remove a small section of skin including deeper layers (epidermis, dermis and superficial fat).
- Excisional biopsy. A doctor uses a small knife (scalpel) to remove an entire lump or an area of abnormal skin, including a portion of normal skin down to or through the fatty layer of skin.
- Alguire PC, et al. Skin biopsy techniques. http://www.uptodate.com/home. Accessed Dec. 28, 2012.
- Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-7234-3541-9..X0001-6--TOP&isbn=978-0-7234-3541-9&uniqId=230100505-57. Accessed Dec. 28, 2012.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 28, 2012.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 14, 2013.


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