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Complications

By Mayo Clinic staff

Because small vessel disease can make it harder for the heart to pump blood to the rest of the body, small vessel disease can cause serious problems if left untreated, such as:

  • Coronary artery spasm
  • Heart attack
  • Sudden cardiac death
  • Heart failure
Preparing for your appointment Risk factors
References
  1. Bairey Merz CN, et al. Syndrome X and microvascular coronary dysfunction. Circulation. 2011;124:1477.
  2. What is coronary microvascular disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/cmd/cmd_all.html. Accessed March 5, 2013.
  3. Camici PC, et al. Coronary microvascular dysfunction. New England Journal of Medicine. 2007;356:830.
  4. Lanza GA, et al. Primary coronary microvascular dysfunction: Clinical presentation, pathophysiology, and management. Circulation. 2010;121:2317.
  5. Cholesterol. Mayo Medical Laboratories. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8320. Accessed March 5, 2013.
  6. Topcu S, et al. Metformin therapy improves coronary microvascular function in patients with polycystic ovary syndrome and insulin resistance. Clinical Endocrinology. 2006;65:75.
  7. Kothawade K, et al. Microvascular coronary dysfunction in women-pathophysiology, diagnosis, and management. Current Problems in Cardiology. 2011;36:291.
  8. Littarru GP, et al. Clinical aspects of coenzyme Q10: An update. Nutrition. 2010;26:250.
  9. Gao L, et al. Effects of coenzyme Q10 on vascular endothelial function in humans: A meta-analysis of randomized controlled trials. Atherosclerosis. 2012;221:311.
  10. Teede HJ, et al. Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy. Fertility and Sterility. 2010; 93:184.
  11. EndoPat overview. Endopat.com. http://endopat.com/Home_Page.html. Accessed March 19, 2013.
  12. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. March 18, 2013.
DS01080 April 9, 2013

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