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Complications
By Mayo Clinic staffBecause small vessel disease can make it harder for the heart to pump blood to the rest of the body, small vessel disease can cause serious problems if left untreated, such as:
- Coronary artery spasm
- Heart attack
- Sudden cardiac death
- Heart failure
References
- Lanza GA, et al. Primary coronary microvascular dysfunction: Clinical presentation, pathophysiology, and management. Circulation. 2010;121:2317.
- What is coronary microvascular disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/cmd/cmd_all.html. Accessed July 10, 2010.
- Beltrame JF, et al. Advances in coronary microvascular dysfunction. Heart, Lung and Circulation. 2009;18:19.
- Camici PC, et al. Coronary microvascular dysfunction. New England Journal of Medicine. 2007;356:830.
- Lakhani K, et al. Microvascular dysfunction in women with polycystic ovary syndrome. Human Reproduction. 2005;20:3219.
- Topcu S, et al. Metformin therapy improves coronary microvascular function in patients with polycystic ovary syndrome and insulin resistance. Clinical Endocrinology. 2006;65:75.
- Foster W, et al. Inflammation and microvascular and macrovascular endothelial dysfunction in rheumatoid arthritis: Effect of treatment. The Journal of Rheumatology. 2010;37:711.
- Kurth T, et al. Migraine and ischaemic vascular events. Cephalalgia. 2007;27:965.
- Coenzyme Q10. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 11, 2010.
- Littarru GP, et al. Clinical aspects of coenzyme Q10: An update. Nutrition. 2010;26:250.
- Hamilton SJ, et al. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes Care. 2009;32:810.
- L-arginine. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 11, 2010.
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