Soft tissue sarcoma


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Risk factors

By Mayo Clinic staff

Living With Cancer

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There aren't many known risk factors for soft tissue sarcomas. But your risk may be increased due to:

  • Age. Soft tissue sarcomas can occur at any age, but overall are more common in older adults. The average age at diagnosis is 57 years. Certain types of sarcomas are more common in children, however.
  • Chemical exposure. Being exposed to certain chemicals, such as vinyl chloride and dioxin, can increase the risk of soft tissue sarcomas.
  • Radiation exposure. Previous radiation treatment for other cancers can increase the risk of soft tissue sarcomas.
References
  1. DeLaney TF. Overview of soft tissue sarcoma. http://www.uptodate.com/home/index.html. Accessed July 21, 2011.
  2. Sinha S, et al. Diagnosis and management of soft tissue sarcoma. British Medical Journal. 2011;342:157.
  3. Detailed guide: Sarcoma — Adult soft tissue cancer. American Cancer Society. http://www.cancer.org/acs/groups/cid/documents/webcontent/003138-pdf.pdf. Accessed July 21, 2011.
  4. Soft tissue sarcomas. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00508. Accessed July 21, 2011.
  5. Lahat G, et al. Sarcoma epidemiology and etiology: Potential environmental and genetic factors. Surgical Clinics of North America. 2008;88:451.
  6. Kenney RJ, et al. Soft tissue sarcomas: Current management and future directions. Surgical Clinics of North America. 2009;89:235.
  7. Thornton K. Chemotherapeutic management of soft tissue sarcoma. Surgical Clinics of North America. 2008;88:647.
  8. Moynihan TJ (expert opinion). Mayo Clinic, Rochester, Minn. July 31, 2011.
DS00601 Sept. 13, 2011

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